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It deubiquitinates TP53/p53 and MDM2 and strongly stabilizes TP53 even in the presence of excess MDM2
leading to increased oxidative phosphorylation and sensitivity to mitochondrial complex I inhibitors
the operation process:
M-CSF receptor is expressed primarily on cells of the monocyte/macrophage lineage
Storage Method: 2-8℃
ASC/TMS1 Rabbit Polyclonal Antibody Apoptosis Detection It deubiquitinates TP53/p53 and MDM2Product Specification Host Rabbit Antigen ASC TMS1 Synonyms Apoptosis associated speck like protein containing a CARD; mASC; PYD and CARD domain containing protein; Pycard Immunogen Recombinant Protein Location Cytoplasm, Nucleus, Mitochondrion, Endoplasmic reticulum Accession Q9EPB4 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Ms, Rt Positive Sample J774A. 1, mouse spleen, rat spleen, rat colon Purification Immunogen