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It is an antigen-presenting glycoprotein that binds and presents both self and microbial lipid and glycolipid antigens to T cells
and complex oligosaccharides
GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions
characterized by two tandem bromodomains (BD1 and BD2) that recognize and bind acetylated lysine residues on histones
This modification can reduce its DNA binding affinity and disrupt its phase separation with 12mer arrays
Choline Acetyltransferase/ChAT Recombinant Rabbit mAb (S-2561-17) Protein Analysis Kits It is an antigen-presenting glycoproteinProduct Specification Host Rabbit Antigen Choline Acetyltransferase ChAT Synonyms Choline O acetyltransferase; CHOACTase; Choline acetylase Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Synapse Accession P28329 Clone Number S 2561 17 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample Human brain, mouse brain, rat brain Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated