UniOne® TR-FRET Human RAK4/CRBN PROTAC Binding KIT Size:2500T while mutations in the β-subunit

while mutations in the β-subunit that impair kinase activity or endocytosis are linked to severe insulin resistance syndromes including Rabson–Mendenhall and type A diabetes

vascular smooth muscle cell proliferation

Species Human Synonyms NC30 Accession P35225 Amino Acid Sequence Protein sequence (P35225

1，G250，Membrane antigen MN，RCC-associated antigen G250 Accession Q8VHB5 Amino Acid Sequence Gln32-Asp390

and endothelial function and has been

UniOne® TR-FRET Human RAK4/CRBN PROTAC Binding KIT Size:2500T while mutations in the β-subunitProduct Specification Host Human Stability & Storage 80 Background This kit utilizes Time Resolved Fluorescence ResonanceEnergy Transfer (TR FRET) technology to measure the interaction between IRAK4and CRBN mediated by the molecular glue PROTAC IRAK4 DEGRADER 1 and testcompounds. This method provides a simple, rapid, and high throughput format fordetecting small molecules capable of mediating IRAK4 CRBN interactions. As shown, the interaction between